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Tanvi Honap

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Tanvi P. Honap

Research Assistant Professor
Ph.D. Arizona State University, 2017

Office: Stephenson Research and Technology Center (SRTC) 1050
Email: tanvi.honap@ou.edu
Phone: (405) 325-7381
Personal Website
lmamr.org

Research Interests

  • Pathogen Evolution
  • Human Microbiome
  • Ancient DNA
  • Genomics
  • Bioinformatics
  • Neglected Tropical Diseases
  • Zoonotic Diseases

Background

Dr. Tanvi Honap is a Research Assistant Professor in the Department of Anthropology and a faculty member of the Laboratories of Molecular Anthropology and Microbiome Research (LMAMR). Her research focuses on studying how human-associated microbial ecologies and pathogens evolve over time.

Dr. Honap received her Ph.D. from Arizona State University in 2017. For her dissertation, she studied the evolutionary histories of the bacteria that cause tuberculosis and leprosy using a paleogenomics approach. She led the first genomic study of leprosy in nonhuman primates (Honap et al. 2018) which found that leprosy strains can be transmitted between humans and other primates in close contact. She has also worked on projects looking at tuberculosis in the pre-colonial era Americas. At LMAMR, Dr. Honap works on projects studying the evolution of the human gut and oral microbiomes. She was recently co-awarded a grant from the National Science Foundation (NSF BCS-2045308) to study oral pathogen evolution.

Recent/Significant Publications

Jacobson DK, Honap TP, Ozga AT, Meda N, Kagone T, Carabin H, Spicer PG, Tito RY, Obregon-Tito A, Reyes LM, Troncoso-Corzo L, Guija-Poma E, Sankaranarayanan K, and Lewis CM (2021). Analysis of global human gut metagenomes shows that metabolic resilience potential for short-chain fatty acid production is strongly influenced by lifestyle. Scientific Reports 11: 1724.

Jacobson DK, Honap TP, Monroe C, Lund J, Houk B, Novotny A, Robin C, Marini E, and Lewis CM (2020). Functional diversity of microbial ecologies estimated from ancient human coprolites and dental calculus. Philosophical Transactions of the Royal Society B 375: 20190586.
 
Honap TP*, Sankaranarayanan K*, Schnorr SL, Ozga AT, Warinner C, and Lewis CM (2020). Biogeographic study of human gut-associated crAssphage suggests impacts from industrialization and recent expansion. PLoS ONE 15(1): e0226930.
 
Honap TP, Pfister L-A, Housman G, Mills S, Tarara RP, Suzuki K, Cuozzo FP, Sauther ML, Rosenberg MS, and Stone AC (2018). Mycobacterium leprae genomes from naturally infected nonhuman primates. PLoS Neglected Tropical Diseases 12(1): e0006190
 
Benjak A*, Honap TP*, Avanzi C, Becerril-Villanueva L, García I, Rojas-Espinosa O, Stone AC, and Cole ST (2017). Insights from the genome sequence of Mycobacterium lepraemurium: massive gene decay and reductive evolution. mBio 8:e01283-17
 
Ozga AT, Nieves-Colón MA, Honap TP, Sankaranarayanan K, Hofman CA, Milner GR, Lewis CM, Stone AC, and Warinner C (2016). Successful enrichment and recovery of whole mitochondrial genomes from ancient human dental calculus. American Journal of Physical Anthropology 160: 220–228.
 
* denotes co-first author

Courses Taught

  • ANTH 5960-23: Directed Reading in Metagenomics.

Curriculum Vitae