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Lee Krumholz, PhD

College of Arts and Sciences, Department of Microbiology and Plant Biology, The University of Oklahoma website wordmark
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Lee Krumholz, PhD

Professor of Microbiology

Lee Krumholz, Ph. D.

616 George Lynn Cross Hall
770 Van Vleet Oval
Norman, OK 73019
405-325-0437 (Office)
405-325-5255 (Lab)

Krumholz Lab Website

B.S. University of Guelph 1982
M.S. University of Illinois 1985. Ph.D. 1988.
Postdoc, Stanford 1988-1990

Research areas:
Microbiology, Molecular and Cellular Biology, Environmental Science, Ecology, Anaerobic Microbiology

Research interests:
My primary area of research is Geomicrobiology, the study of bacteria and their interaction with rocks and sediments. I am currently directly involved in two major projects, focusing on the actions of anaerobic bacteria including sulfate reducing bacteria (SRB). The most important role of anaerobic bacteria is in biodegradation of organic matter in subsurface aquifers and in coastal marine sediments as well as in respiration of alternative electron acceptors. The following are the funded projects on which my students and I are currently working (1) Studies of genes from sulfate reducing bacteria specifically used in syntrophic interactions. We employ a signature tagged mutagenesis approach to identify functional genes used for syntrophic growth. These techniques allow us to develop an understanding of the metabolism of SRB and their interaction with the natural environment. This project is currently funded through DOE. (2) Microbial ecology of a natural sulfide spring in Western Oklahoma. This project uses both molecular ecology, genomics and more traditional microbial ecology techniques to explore the biodiversity of a unique Oklahoma ecosystem. The goal of the project is to discover new microorganisms and develop a better understanding of the function of this unique ecosystem. This project was recently funded through a National Science Foundation grant for a Microbial Observatory at Zodletone Spring Oklahoma.

Relevant publications:

Li , X., M.J. McInerney, D.A. Stahl and L.R. Krumholz. 2011. Metabolism of H2 by Desulfovibrio desulfuricans G20 During Syntrophic Growth on Lactate. Microbiology. Microbiology. 157:2912-2921.

Sheik, C.S., W.H. Beasley, M.S. Elshahed, X. Zhou, Y. Luo and L.R. Krumholz. 2011. Effect of warming and drought on grassland microbial communities. ISME J. 1-9.

Savage, K.N., L.R. Krumholz, L.M. Gieg, V.A. Parisi, J.M. Suflita, J. Allen, R. P. Philp and M.S. Elshahed. 2010. Biodegradation of low molecular weight alkanes under mesophilic, sulfate-reducing conditions: metabolic intermediates and community patterns. FEMS Microbiology. Lett. 72(3): 485–495.

Li, X. and L.R. Krumholz. 2009. Thioredoxin is Involved in U(VI) and Cr(VI) Reduction in Desulfovibrio desufuricans G20. J. Bacteriol. 191: 4924–4933.

Spain, A.M., L.R. Krumholz and M.S. Elshahed. 2009. Abundance, Composition, Diversity, and Novelty of Soil Proteobacteria ISME J. 3(8):992-1000.