Randall S. Hewes
Associate Professor & Assistant Chair
Zoology
Stephenson Technology & Research Center 2021
405-325-6099
hewes at ou dot edu
http://www.edrosophila.com/
Ph.D., Zoology - University of Washington, 1993
Research:
The research in my lab is focused on the plasticity of neuroendocrine signaling, with special attention to neuropeptide and peptide hormone (peptidergic) systems and their roles in animal behavior.
Selected Publications:
Hewes, R. S. (2008) The buzz on fly neuronal remodeling. Trends Endocrinol. Metabolism, 19: 317-323.
Zhao, T., Gu, T., Rice, H. C., McAdams, K. L., Roark, K. M., Lawson, K., Gauthier, S. A., Reagan, K. L., & Hewes, R. S. (2008). A Drosophila gain-of-function screen for candidate genes controlling steroid-dependent neuroendocrine cell remodeling. Genetics, 178: 883-901.
Shakiryanova, D., Klose, M., Zhou, Y., Gu, T., Deitcher, D. L., Atwood, H. L., Hewes, R. S. & Levitan, E. S. (2007) Presynaptic ryanodine receptor-activated calmodulin kinase II increases vesicle mobility and potentiates neuropeptide release. J. Neurosci., 27: 7799-7806.
Hewes, R. S., Gu, T., Brewster, J. A., Qu, C. & Zhao, T. (2006) Regulation of secretory protein expression in mature cells by DIMM, a bHLH neuroendocrine differentiation factor. J. Neurosci., 26: 7860-7869.
Gauthier, S. A., & Hewes, R. S. (2006) Transcriptional regulation of neuropeptide and peptide hormone expression by the Drosophila dimmed and cryptocephal genes. J. Exp. Biol., 209: 1803-1815.
Sturman, D. A., Shakiryanova, D., Hewes, R. S., Deitcher, D. L. & Levitan, E. S. (2006) Nearly neutral secretory vesicles in Drosophila nerve terminals. Biophysical Journal, 90: L45-L47.
Shakiryanova, D., Tully, A., Hewes, R. S., Deitcher, D. L. & Levitan, E. S. (2005) Activity-dependent liberation of synaptic neuropeptide vesicles. Nat. Neurosci., 8():173-178. (pdfs). Faculty of 1000 rating: 3.0.