Yunpeng Lan

Major Professor: Yang
Email: yunpeng.lan-1@ou.edu

Hometown:
Shijiazhuang, Hebei, China

High School:
Shijiazhuang No.41 Middle School

Education:
B.S., Polymer Science and Engineering, Sichuan University, China

The prerequisite of learning chemistry in university was to study science branch in middle school. In middle school I know chemical branches such as theoretical chemistry, inorganic chemistry, organic chemistry, and analytic chemistry. The world became rich, and I had been aware that knowledge I had had was very limited. I cannot be master for all of them. In the end, because of advice from my middle school’s teachers, I chose my major at chemistry.

I am currently working with Dr. Zhibo Yang in analytical chemistry division and I am focusing on mass spectrometry single cell metabolomics, drug quantification, small molecule quantitation in single cell and cancer related study. I am currently having two projects, Quantitative Detection of Nitric Oxide (NO) from Single Cells and Quantitative analysis of anticancer drugs in single multicellular spheroids.

After graduation, I plan to find a job in industry.

Publications, Presentations & Awards

Publications

Nguyen, T. D.*; Lan, Y.*; Kane, S. S.; Haffner, J. J.; Liu, R.; McCall, L.-I.; Yang, Z., Single-Cell Mass Spectrometry Enables Insight into Heterogeneity in Infectious Disease. Analytical Chemistry 2022, 94 (30), 10567-10572.
Nguyen, T.D.*; Lesani, M.*; Forrest, I.*; Lan, Y.*; Dean, D.A.; Gibaut, Q.M.R.; Guo, Y.; Hossain, E.; Olvera, M.; Panlilio, H.; Parab, A.R.; Wu, C.; Bernatchez, J.A.; Cichewicz, R.H.; McCall, L.-I. Local Phenomena Shape Backyard Soil Metabolite Composition. Metabolites 2020, 10, 86 (2020). https://www.mdpi.com/2218-1989/10/3/86
Liu R, Sun M, Zhang G, Lan Y, Yang Z. Towards early monitoring of chemotherapy-induced drug resistance based on single cell metabolomics: Combining single-probe mass spectrometry with machine learning. Anal Chim Acta. 2019 Dec 27;1092:42-48. PubMed Central PMCID: PMC6878984.
Moen, E. L., Lam, A. K., Pusavat, J., Wouters, C. L., Panlilio, H., Heydarian, N., Peng, Z., Lan, Y., & Rice, C. V. (2022). Dimerization of 600 Da branched polyethylenimine improves β-lactam antibiotic potentiation against antibiotic-resistant Staphylococcus epidermidis and Pseudomonas aeruginosa. Chemical Biology & Drug Design, 00, 1– 11. https://doi.org/10.1111/cbdd.14009

Presentations

Oral Presentations

Lan, Y.*, Nguyen, T.D.*, Liu, R., Kane, S.S., McCall, L.-I., Yang, Z. Single cell mass spectrometry metabolomics studies of cell heterogeneity in the infection of Chagas disease. The 68th American Society for Mass Spectrometry, Houston, TX (2020).
Lan, Y. Xingxiu Chen, Zhibo Yang. Quantification of Nitric Oxide (NO) in Single Cells using Mass Spectrometry. The 59th Lake Arrowhead Ion Chemistry and Mass Spectrometry. Lake Arrowhead, CL (2022)

Poster Presentations

Yunpeng Lan, Xingxiu Chen, Zhibo Yang. Quantification of Nitric Oxide (NO) in Single Cells using Mass Spectrometry. Chinese American Society for Mass Spectrometry (CASMS), 2022.
Yunpeng Lan, Zhibo Yang. Single Cell Metabolomics of Primary and metastatic Melanoma Cancer Cells by Using Micropipette. The 2021 Annual Cancer Research Symposium, OUHSC, 2021.

Grants, Honors & Awards

Dodge Family College of Arts and Sciences Graduate research fellowship, University of Oklahoma, Spring 2023
Third at the Annual Cancer Research Symposium, OU Health Stephenson Cancer Center, Spring 2022
Graduate Student Senate Grant, University of Oklahoma, Spring 2022
Robberson Travel Grant, University of Oklahoma, Spring 2022
Robberson Research Grant, University of Oklahoma, Spring 2021