110 W. Boyd Street
Norman, OK 73019
Ph.D., 2006, University of Tennessee, Knoxville, TN
B.S., 2001, East China Normal University, Shanghai, China
Bioinformatics, Machine Learning, Proteomics, Environmental Microbiomes, Human Microbiomes, Prebiotics and Probiotics
My research spans Computer Science (in the areas of explainable machine learning and parallel computing for biomedical informatics) and Microbiology (in the areas of human microbiomes and environmental microbiomes). In human microbiomes, I am interested in understanding the beneficial impacts of probiotics and prebiotics on human health. In environmental microbiomes, I am interested in developing mechanistic models of wetland sediment communities to predict their emission of greenhouse gases in future climate regimes. Our approaches include computational biology, proteomic stable isotope probing, integrated -omics, and synthetic microbiomes.
Z. Li, Q. Yao, X. Guo, A. Crits-Christoph, M.A. Mayes, W.J. Hervey, S.L. Lebeis, J.F. Banfield, G.B. Hurst, R.L. Hettich, C. Pan (2019) Genome-Resolved Proteomic Stable Isotope Probing of Soil Microbial Communities Using 13CO2 and 13C-Methanol. Frontier in Microbiology 10:2706. doi: 10.3389/fmicb.2019.02706
S. Diamond, P. Andeer, Z. Li, A. Crits-Christoph, D. Burstein, K. Anantharaman, K.R. Lane, B.C. Thomas, C. Pan, T. Northen and J.F. Banfield (2019) Mediterranean Grassland Soil C-N Compound Turnover is Mediated by Genomically Divergent Organisms, Depth Stratified, and Rainfall Dependent. Nature Microbiology 4(8):1356-1367
Q. Yao, Z. Li, Y. Song, S. J. Wright, X. Guo, S. G. Tringe, M.M. Tfaily, L. Paša-Tolic, T. C. Hazen, B. L. Turner, M. A. Mayes, C. Pan (2018) Community Proteogenomics Reveals the Systemic Impact of Phosphorus Availability on Microbial Functions in Tropical Soil. Nature Ecology and Evolution 2(3):499-509
X. Guo, Z. Li, Q. Yao, R.S. Mueller, J. K. Eng, D. L. Tabb, W. J. Hervey, and C. Pan (2018) Sipros Ensemble Improves Database Searching and Filtering for Complex Metaproteomics, Bioinformatics 34(5):795-802.
Z. Li, Y. Wang, Q. Yao, N. B. Justice, T.-H. Ahn, D. Xu, R. L. Hettich, J. F. Banfield, and C. Pan. (2014) Diverse and divergent protein post-translational modifications in two growth stages of a natural microbial community, Nature Communications 5:4405. doi: 10.1038/ncomms5405