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Chung-Hao Lee

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Chung-Hao Lee

Assistant Professor

EDUCATION

Ph.D., Civil Engineering (Structural and Computational Mechanics), UCLA (December 2011)

M.S., Civil Engineering (Structural Engineering), National Taiwan University (June 2005)

B.S., Civil Engineering, National Taiwan University (June 2003)

RESEARCH INTERESTS

  • Multiscale biomechanical modeling of the cardiovascular systems – heart valves
  • Characterization of structural and mechanical properties of soft biological tissues
  • Patient-specific modeling for improved diagnosis and prophylactic disease management
  • Shape memory polymer-based embolization device development for intracranial aneurysms
  • Advanced finite element and meshfree methods for image-based computational biomechanics

HONORS AND AWARDS (selected)

  • OU Nancy L. Mergler Faculty Mentor Award for Undergraduate Research, 2018
  • OU VPR Faculty Investment Program Award AY2018
  • OU VPR Faculty Investment Program Award AY2017
  • American Heart Association (AHA) Scientist Develop Grant (SDG), 07/2016–06/2020
  • American Heart Association (AHA) Postdoctoral Fellowship, 01/2014–12/2015
  • First Place Winner for the Dimitris N. Chorafas Foundation Awards, 2011
  • UCLA Dissertation Year Fellowship, 09/2010–08/2011

COURSES TAUGHT
The University of Oklahoma

  • AME 3112 Solid Mechanics Lab (Fall 2019, Fall 2020)
  • AME 3143 Solid Mechanics (Summer 2019)
  • AME 5213/4213, BME 5213 Biomechanics I (Spring 2017, Spring 2018, Spring 2019)
  • AME 3723 Numerical Methods for Engineering Computation (Fall 2016, Fall 2017)

The University of Texas at Austin

  • ASE 301 Introduction to Computer Programming (Fall 2015)

PROFESSIONAL EXPERIENCE

  • 01/2017-Present, Affiliated Faculty Member, Institute for Biomedical Engineering, Science and Technology (IBEST), The University of Ok
  • 08/2016-Present, Assistant Professor, School of Aerospace and Mechanical Engineering, The University of Oklahoma, Norman, OK
  • 02/2012-07/2016, ICES & AHA Postdoctoral Fellow, Institute for Computational Engineering and Sciences (ICES), The University of Texas at Austin, Austin, TX
  • 09/2015-01/2016, Adjunct Lecturer, Department of Aerospace Engineering and Engineering Mechanics, The University of Texas at Austin, Austin, TX
  • 09/2007-12/2011, Graduate Research Assistant, UCLA, Los Angeles, CA

SELECTED JOURNAL PUBLICATIONS (*denotes mentored students/researchers) 

  • Kramer, K.E.*, Ross, C.J.*, Laurence, D.W.*, Babu, A.R.*, Wu, Y.*, Towner, R.A., Mir, A., Burkhart, H.M., Holzapfel, G.A., and Lee, C.-H., “An investigation of layer-specific tissue biomechanics of porcine atrioventricular valve anterior leaflets,” Acta Biomaterialia (Accepted, In Press).
  • Ross, C.J.*, Laurence, D.W.*, Richardson, J.*, Babu, A.R.*, Evans, L.E.*, Beyer, E.G.*, Childers, R.C., Wu, Y.*, Towner, R.A., Fung, K.-M., Mir, A., Burkhart, H.M., Holzapfel, G.A., and Lee, C.-H., “An investigation of the glycosaminoglycan contribution to biaxial mechanical behaviors of porcine atrioventricular heart valve leaflets,” Journal of the Royal Society Interface, 16(156), 20190069.
  • Lee, C.-H., Laurence, D.W.*, Ross, C.J.*, Kramer, K.E.*, Babu, A.R.*, Johnson, E.L., Hsu, M.-C.§, Aggarwal, A., Mir, A., Burkhart, H.M., Towner, R.A., Baumwart, B., and Wu, Y.*, “Mechanics of the tricuspid valve-From clinical diagnosis/treatment, in-vivo and in-vitro investigations, to patient-specific biomechanical modeling,” Bioengineering, 6(2), 47 (40 pages), 2019.
  • Wang, J., Luo, J., Li, Kunkel, R.P.*, Saha, M., Bohnstedt, B.N., Lee, C.-H., and Liu, Y. “Development of shape memory polymer nanocomposite foam for treatment of intracranial aneurysms,” Materials Letters, 250, 38-41, 2019.
  • Laurence, D.W.*, Ross, C.J.*, Jett, S.V.*, Johns, C.H.*, Echols, A.L.*, Baumwart, R., Towner, R.A., Liao, J., Bajona, P., Wu, Y.#, and Lee, C.-H.*, “Regional biaxial mechanical data of the mitral and tricuspid valve anterior leaflets,” Data in Brief, 24, 103961, 2019.
  • Wang, J., Kunkel, R.P.*, Luo, J., Li, Y., Liu, H., Bohnstedt, B.N., Liu, Y., and Lee, C.-H., “Shape memory polyurethane with porous architectures for potential applications in intracranial aneurysm treatment,” Polymers, 11(4), 631, 2019.
  • Laurence, D.W.*, Ross, C.J.*, Jett, S.V.*, Johns, C.H.*, Echols, A.L.*, Baumwart, R., Towner, R.A., Liao, J., Bajona, P., Wu, Y.*, and Lee, C.-H., “An investigation of regional variations in the biaxial mechanical properties and stress relaxation behaviors of porcine atrioventricular heart valve leaflets,” Journal of Biomechanics, 83: 16-27, 2019.
  • Ross, C.J.*, Laurence, D.W.*, Wu, Y.*, and Lee, C.-H., “Biaxial mechanical characterization of atrioventricular heart valves,” Journal of Visualized Experiments, 146: e59170, 2019.
  • Jett, S.V.*, Laurence, D.W.*, Kunkel, R.P.*, Babu, A.R.*, Kramer, K.E.*, Baumwart, R., Towner, R.A., Wu, Y.*, and Lee, C.-H., “Biaxial mechanical data of porcine atrioventricular valve leaflets,” Data in Brief, 21: 358-363, 2018.
  • Kunkel, R.P.*, Laurence, D.W.*, Wang, J., Robinson, D.O.*, Scherrer, J.H.*, Wu, Y.*, Bohnstedt, B.N., Chien, A., Liu, Y., and Lee, C.-H., “Synthesis and characterization of bio-compatible shape memory polymers with potential applications to endovascular embolization of intracranial aneurysms,” Journal of the Mechanical Behavior of Biomedical Materials, 88: 422-430, 2018.
  • Jett, S.V.*, Laurence, D.W.*, Kunkel, R.P.*, Babu, A.R.*, Kramer, K.E.*, Baumwart, R., Towner, R.A., Wu, Y.*, and Lee, C.-H., “An investigation of the anisotropic mechanical properties and anatomical structure of porcine atrioventricular heart valves,” Journal of the Mechanical Behavior of Biomedical Materials, 87: 155-171, 2018.
  • Kamensky, D., Xu, F., Lee, C.-H., Yan, J., Bazilevs, Y., and Hsu, M.-C., “A new contact formulation based on a volumetric potential: Application to isogeometric simulations of atrioventricular valves,” Computer Methods in Applied Mechanics and Engineering, 330(1): 522-546, 2018.
  • Ayoub, S., Lee, C.-H., Driesbaugh, K.H., Anselmo, W., Hughes, C.T., Ferrari, G., Gorman, R.C., Gorman, J.H., III, and Sacks, M.S., “Regulation of valve interstitial cell homeostasis by mechanical deformation: Implications for heart valve disease and surgical repair,” Journal of Royal Society – Interface, 14(135): 20170580, 2017.
  • Lee, C.-H., Zhang, W., Feaver, K., Gorman, R.C., Gorman, J.H., III, and Sacks, M.S., “On the in vivo function of the mitral heart valve leaflet: insight into tissue-interstitial cell biomechanical coupling,” Biomechanical Modeling and Mechanobiology, 16(5): 1613-1632, 2017.
  • Feng, Y., Qiu, S., Xia, X., Ji, S., and Lee, C.-H., “A computational study of invariant I5 in a nearly incompressible transversely isotropic model for white matter,” Journal of Biomechanics, 57: 146-151, 2017.
  • Rego, B.V., Wells, S.M., Lee, C.-H., and Sacks, M.S., “Mitral valve remodeling during pregnancy: insights into cell-mediated recovery of tissue homeostasis,” Journal of the Royal Society Interface, 13(125): 20160709, 2016.
  • Lee, C.-H., Rabbah, J.P., Yoganathan, A.P., Gorman, R.C., Gorman, J.H., III, and Sacks, M.S., “On the effect of leaflet microstructure and constitutive model on the closing behavior of the mitral valve.” Biomechanical Modeling and Mechanobiology, 14(6): 1281-1302, 2015.
  • Lee, C.-H., Zhang, W., Carruthers, C.A., Sacks, J.I., and Sacks, M.S., “On the presence of affine fiber and fibril kinematics in the mitral valve anterior leaflet under simulated physiological loading.” Biophysical Journal, 108(8): 2074-2087, 2015.
  • Lee, C.-H., Carruthers, C.A., Ayoub, S., Gorman, R.C., Gorman, J.H., III, and Sacks, M.S., “Quantification and simulation of the layer-specific mitral valve interstitial cell deformations under physiological loading.” Journal of Theoretical Biology, 373: 26-39, 2015.
Chung-Hao Lee

Contact Information

(405) 325-4842
Felgar Hall 219C
ch.lee@ou.edu
View Curriculum Vitae (PDF)

Office Hours:

Biomechanics: Tuesdays and Thursdays 1:15 PM - 1:45 PM

General: Wednesdays 9:30 AM - 10:30 AM 

Also by appointment

Biomechanics & Biomaterials Design Laboratory

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