Oklahoma COBRE in Structural Biology

How to acknowledge COBRE support:

"Research reported in this [publication, release] was supported by Institutional Development Awards (IDeA) from the National Institute of General Medical Sciences of the National Institutes of Health under grant numbers P20GM103640 and P30GM145423."

Contact

Ann H. West
Stephenson Life Sciences Research Center
101 Stephenson Parkway
Norman, OK 73019

Phone: 405-325-1529
Email: awest@ou.edu

"May We Have Peace" bronze statue by Allan Houser

"May We Have Peace" bronze statue of Native American holding a peace pipe by Allan Houser is located on the North Oval of the OU campus

Oklahoma COBRE in Structural Biology

Welcome to the website of the Oklahoma Center of Biomedical Research Excellence in Structural Biology (OCSB). This NIH-funded center supports research groups on the OU-Norman and OUHSC campuses that utilize a structural approach to study important biological macromolecules, in particular, proteins or nucleic acids that are promising targets for rational drug design.

Structural biology lies at the intersection of many different areas of biological sciences and thus has the potential of impacting numerous biomedically important fields. The OCSB was established in 2012 with an NIH COBRE Phase I award (1P20GM103640-01) and a Phase II renewal grant (2P20GM103640-06) was awarded 2017.

In May 2022, the OCSB was awarded the NIH COBRE Phase 3 grant (P30GM145423) which will continue to provide resources for investigators at OU, OUHSC, and other institutions throughout the State of Oklahoma for structure-based biomedical studies as well as guide the OCSB-supported core facilities to a sustainable future.

View the OCSB COBRE's publications on PubMed.gov.

New Equipment

The Protein Production and Characterization Core (PPCC) facility in Norman now has a BioTek Synergy H1 Microplate Reader available. The instrument features monochromator-based optics and filter-based optics and continuously variable bandwidth monochromators for fluorescence excitation and emission wavelength selection. More information can be found here.

The Biomolecular Structure Core (BSC) facility in Norman has a new Formulatrix Rock Imager available to use for storing and viewing crystallization trials. It is equipped with UV imaging and Multi-Fluorescence Imaging (MFI) technology. More information can be found here.

Events

COBRE Group Meetings Fall 2022

Tuesday, September 20, 2 pm (via ZOOM) Presenting: PPCC

Thursday, October 27, 1:30 pm (via ZOOM) Presenting: BSC

EAC Meeting

The next EAC meeting will take place January 12-13, 2023.

The June 2023 EAC meeting is scheduled for June 1-2, 2023