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Oklahoma COBRE in Structural Biology

3D Rendering of a protein
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Oklahoma COBRE in Structural Biology


Welcome to the website of the Oklahoma Center of Biomedical Research Excellence in Structural Biology (OCSB). This NIH-funded center supports research groups on the OU-Norman and OUHSC campuses that utilize a structural approach to study important biological macromolecules, in particular, proteins or nucleic acids that are promising targets for rational drug design.

Structural biology lies at the intersection of many different areas of biological sciences and thus has the potential of impacting numerous biomedically important fields. The OCSB was established in 2012 with an NIH COBRE Phase I award (1P20GM103640-01) and a Phase II renewal grant (2P20GM103640-06) was awarded 2017. 

In May 2022, the OCSB was awarded the NIH COBRE Phase 3 grant (P30GM145423) which will continue to provide resources for investigators at OU, OUHSC, and other institutions throughout the State of Oklahoma for structure-based biomedical studies as well as guide the OCSB-supported core facilities to a sustainable future.

View the OCSB COBRE's publications on

Events and Dates

Free workshop: Phenix Software for Macromolecular Structure Determination

Presented by Phenix Developers and sponsored by Oklahoma COBRE in Structural Biology

Monday & Tuesday, March 18-19, 2024, 8:30 am - 5:00 pm each day, in person. Breakfast and lunch will be provided.
Location: University of Oklahoma, Stephenson Life Sciences Research Center

The agenda for the workshop, including the presenters, can be found here.

The flyer for the workshop can be found here.

Registration is now open and can be found here. (Deadline is February 23, 2024)

COBRE Group Meetings Spring 2024: 

Tuesday, February 27, 2024, 9:00-10:00 am - Presenting: Y. Shao and V. Somalinga
Thursday, March 14, 2024, 9:30-10:30 am - Presenting: PPCC
Thursday, April 18, 2024, 9:00-10:00 am - Presenting: E. Lutter and A. Burgett
Thursday, May 2, 2024, 9:30-10:30 am - Presenting: BSC

EAC Meeting

The next EAC meeting will take place Thursday, June 13, 2024.