Farnaz Zamani Esfahlani
Assistant Professor, Biomedical EngineeringBrain Organization and Network Dynamics (BOND) Lab Gallogly Hall 307 405-325-6246 fzamani at ou dot edu https://bond-lab.com/ Systems Science - State University of New York at Binghamton, 2018RESEARCH:
At the Brain Organization and Network Dynamics (BOND) Lab, we study brain connectivity and its relationship to cognition and behavior. Our research aims to understand the role of both structural and functional connectivity in supporting typical cognitive functions and examine how disruptions in these connectivity patterns contribute to the cognitive deficits observed in conditions such as psychosis and autism spectrum disorders.
To achieve these goals, we use a combination of neuroimaging, including fMRI and EEG, behavioral and computational approaches, to characterize the network architecture’s underlying typical and atypical cognitive functions, such as emotion, working memory and inhibitory control.
With the insights obtained from the theoretical and data-driven analysis of brain connectivity, our goal is to identify network-level biomarkers for early diagnosis and treatment of neuropsychiatric and neurodevelopmental disorders.
Selected Publications:
Esfahlani, F. Z., Byrge, L., Tanner, J., Sporns, O., Kennedy, D. P., and Betzel, R. F. (2022) Edge-centric analysis of time-varying functional brain networks with applications in autism spectrum disorder. NeuroImage 263: 119591.
Zamani Esfahlani, F., Faskowitz, J., Slack, J., Mišić, B., and Betzel, R. F. (2022)Local structure-function relationships in human brain networks across the lifespan. Nature Communications 13(1): 1-16.
Zamani Esfahlani, F., Jo, Y., Faskowitz, J., Byrge, L., Kennedy, D. P., Sporns, O., and Betzel, R. F. (2020) High-amplitude cofluctuations in cortical activity drive functional connectivity. Proceedings of the National Academy of Sciences 117(45): 28393-28401.
Faskowitz, J., Zamani Esfahlani, F., Jo, Y., Sporns, O., and Betzel, R. F. (2020) Edge-centric functional network representations of human cerebral cortex reveal overlapping system-level architecture. Nature Neuroscience 23(12): 1644-1654.
Jo, Y., Zamani Esfahlani, F., Faskowitz, J., Chumin, E., Sporns, O., and Betzel, R. (2020) The diversity and multiplexity of edge communities within and between brain systems. Cell Reports 37(7): 110032.
Zamani Esfahlani, F., Bertolero, M. A., Bassett, D. S., and Betzel, R. F. (2020) Space-independent community and hub structure of functional brain networks. NeuroImage 211: 116612.
Zamani Esfahlani, F., Visser, K.,Strauss, G., and Sayama, H. (2018) A Network Based Classification Framework to Predict Treatment Response of Schizophrenia Patients. Expert Systems with Applications 109 (C): 152 - 161.
Strauss, G. P., Zamani Esfahlani, F., Visser, K. F., Dickinson, E. K., Gruber, J., and Sayama, H. (2019) Mathematically modeling emotion regulation abnormalities during psychotic experiences in schizophrenia. Clinical Psychological Science 7(2): 216-233.