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The Department of Surgery has been involved in basic science, translational, investigator initiated, and clinical trials for many years. Each year our residents and faculty have had a strong presence in OU Tulsa’s annual Research Forum where we have won many awards. We are proud of the contribution our faculty and residents have made in their research endeavors.

The OU Vascular Clinic has been very active in 2020, and many opportunities have arisen for our trainees over the last year. The department has published 36 peer-reviewed journal articles and a patent on therapeutics to the spinal cord in spinal cord pathology. Additionally, the department has conducted 37 presentations on the local, regional, and national levels, and is involved in a number of clinical trials. Below is a list of current publications and ongoing clinical trials. 

Peer-reviewed journal articles

1   Guo, X., Eitnier, R.A., Beard, Jr., R.S., Meegan, J., Yang, X.A., Wang, F.A., Aponte, A., Nelson, P., Wu, M. H. (2019). Focal adhesion kinase and Src mediate microvascular hyperpermeability caused by fibrinogen-γ C- terminal fragments. PLoS One. PMID: 32352989.

2   Pandit, V., Zeeshan, M., Nelson, P., Hamidi, M., Jhajj, S., Lee, A., Trinidad, B., Goshima, K., Horst, V., Weinkauf, C., Zhou, W., Tan, T.-W. (2019). Frailty Syndrome in Patients with Carotid Disease: Simplifying How We Calculate Frailty. Annals of Vascular Surgery. DOI: 10.1016/j.avsg.2019.10.001. PMID: 31610278.

3   He, Y., DeSart, K., Kubilis, P. S., Irwin, A., Tan-Son-Tay, R., Nelson, P., Berceli, S. A. (2019). Heterogeneous and Dynamic Lumen Remodeling of the Entire Infrainguinal Vein Bypass Grafts in Patients. Journal of Vascular Surgery. DOI: 10.1016/j.jvs.2019.05.069. PMID: 31611109.

4  Anderson, P. B., Wanken, Z. J., Perri, J. L., Columbo, J. A., Kang, R., Spangler, E. L., Newhall, K., Brooke, B. S., Dosluoglu, H., Lee, E. S., Rafetto, J. D., Henke, P. K., Tang, G. L., Mureebe, L., Kougias, P., Johanning, J., Arya, S., Scali, S. T., Stone, D. H., Suckow, B. D., Orion, K., Halpern, V., O'Connell, J., Inhat, D., Nelson, P., Tzeng, E., Zhou, W., Barry, M., Sirovich, B., Goodney, P. P. (2019). Patient information sources when facing repair of abdominal aortic aneurysm. Journal of Vascular Surgery. DOI: 10.1016/j.jvs.2019.04.460. PMID: 31353272.

5  Jackson, T., Zhou, C., Khorgami, Z., Jackson, D., Agarwal, V., Taubman, K. E., Nelson, P., Truitt, M. (2019). Traumatized Residents - It's not surgery.  It's medicine. Journal of Surgical Education. DOI: 10.1016/j.jsurg.2019.08.002. PMID: 31477549.

6 Lederle, F. A., OVER VA Cooperative Study Group, Nelson, P. (2019). Open Versus Endovascular Repair of Abdominal Aortic Aneurysm. New England Journal of Medicine, 380(22), 2126-2135. PMID: 31141634.

7  Columbo, J. A., Kang, R., Spangler, E. L., Newhall, K., Brooke, B. S., Dosluoglu, H., Lee, E. S., Rafetto, J. D., Henke, P. K., Tang, G. L., Mureebe, L., Kougias, P., Johanning, J., Arya, S., Scali, S. T., Stone, D. H., Suckow, B. D., Orion, K., Halpern, V., O'Connell, J., Inhat, D., Nelson, P., Tzeng, E., Zhou, W., Barry, M., Sirovich, B., Goodney, P. P. (2019). Design of Preferences for Open Versus Endovascular Repair of Abdominal Aortic Aneurysm (PROVE-AAA) Trial. Annals of Vascular Surgery. DOI: 10.1016/j.avsg.2019.02.034. PMID: 31075459.

8  Tanious, A., Karunathilake, N., Toro, J., Hanna, A., Fawcett, T., Graves, B., Nelson, P. (2019). Racial Disparities in Endovascular Aortic Aneurysm Repair. Annals of Vascular Surgery.  DOI: 10.1016/j.avsg.2018.11.002. PMID: 30476598.

9  Kougias, P., Biswas, K., Mi, Z., Carson, J. L., Dosluoglu, H., Nelson, P., Sarosi, G., Arya, S., Sharath, S., Scrymgeour, A. Transfusion Trigger After Operations in High Cardiac Risk Patients (TOP) Trial Protocol (2019). Development of a Multicenter Randomized Controlled Transfusion Strategy Trial. Journal of the American Medical Association Surgery.

10  Jennings, W.C., Nelson, P.R. (2020). The role of precision banding of arteriovenous fistulas in successful kidney transplant recipients (2nd ed., vol. 71, pp. 719). Journal of Vascular Surgery. DOI:10.1016/j.jvs.2019.10.026. PMID: 32040439.

11   Mallios, A., Nelson, P.R., Franco, G, Jennings, W.C. Creating percutaneous radiocephalic arteriovenous fistulas at the wrist. J Vasc Access. 2020 Jun 27:1129729820933737. DOI: 10.1177/1129729820933737. Online ahead of print. PMID: 32597355. 

12   Beathard, G.A., Litchfield, T., Jennings, W.C. Two-year cumulative patency of endovascular arteriovenous fistula. J Vasc Access. 2020 May;21(3):350-356. DOI: 10.1177/1129729819877780. Epub 2019 Sep 28. PMID: 31566061.

13  Beathard, G.A., Jennings, W.C., Wasse, H., Shenoy, S., Hentschel, D.M., Abreo, K., Urbanes, A., Nassa,r G., Dolmatch, B., Davidson, I., Asif, A.  ASDIN white paper: Assessment and management of hemodialysis access-induced distal ischemia by interventional nephrologists. J Vasc Access. 2020 Sep;21(5):543-553. DOI: 10.1177/1129729819894774. Epub 2019 Dec 30. PMID: 31884872.

14  Mallios, A., Beathard, G.A., Jennings, W.C. Early cannulation of percutaneously created arteriovenous hemodialysis fistulae. J Vasc Access. 2019 Dec 19:1129729819892796. DOI: 10.1177/1129729819892796. Online ahead of print. PMID: 31854231. 

15  Wasse, H., Alvarez, A.C., Brouwer-Maier, D., Hull, J.E., Balamuthusamy, S., Litchfield, T.F., Cooper, R.I., Rajan, D.K., Niyyar, V.D., Agarwal, A.K., Abreo, K., Lok, C.E., Jennings, W.C.  Patient selection, education, and cannulation of percutaneous arteriovenous fistulae: An ASDIN White Paper. J Vasc Access. 2019 Nov 29:1129729819889793. DOI: 10.1177/1129729819889793. Online ahead of print. PMID: 31782685.

16  Mallios, A. Bourquelot, P., Harika, G., Boura, B., Jennings, W.C. Percutaneous creation of proximal radio-radial arteriovenous hemodialysis fistula before secondary brachial vein elevation. J Vasc Access. 2020 Jun 27:1129729820936921. DOI: 10.1177/1129729820936921. Online ahead of print. PMID: 32597359.

17  Mallios, A., Bourquelot, P., Jennings, W.C. The challenge of stent placement within cannulation zones of Arteriovenous Fistulae. J Vasc Access. 2020 Sep 4:1129729820954741. DOI: 10.1177/1129729820954741. Online ahead of print. PMID: 32883152.

18  Mallios, A., Bourquelot, P., Franco, G., Hebibi, H., Fonkoua, H., Allouache, M., Costanzo, A., de Blic, R., Harika, G., Boura, B., Jennings, W.C. Midterm results of percutaneous arteriovenous fistula creation with the Ellipsys Vascular Access System, technical recommendations , and an algorithm for maintenance. J Vasc Surg. 2020 Apr 8:S0741-5214(20)30476-6. DOI: 10.1016/j.jvs.2020.02.048. Online ahead of print. PMID: 32276012.

19  Mallios, A., Jennings, W.C. Endovascular Revision Using Distal Inflow: EndoRUDI. Eur J Vasc Endovasc Surg. 2020 Jul:60(1):144. DOI: 10.1016/j.ejvs.2020.03.050. Epub 2020 May 12. PMDI: 32409014.

20  Franco G, Mallios A, Bourquelot P, Hebibi H, Jennings W, Boura B. Feasibility for arteriovenous fistula creation with Ellipsys ®  J Vasc Access. 2020 Sep;21(5):701-704. doi: 10.1177/1129729819900114. Epub 2020 Jan 13. PMID: 31928135.

21  Franco G, Mallios A, Bourquelot P, Jennings W, Boura B. Ultrasound evaluation of percutaneously created arteriovenous fistulae between radial artery and perforating vein at the elbow. J Vasc Access. 2020 Sep;21(5):694-700. doi: 10.1177/1129729819897654. Epub 2020 Jan 10. PMID: 31920156.   

22  Mallios A, Jennings WC. Percutaneously created sutureless anastomosis  J Vasc Surg Cases Innov Tech. 2020 Jul 15;6(4):498-499. doi: 10.1016/j.jvscit.2020.05.015. eCollection 2020 Dec. PMID: 33134629.

23  Horst, V.D., Nelson, P.R., Mallios, A., Kempe, K., Pandit, V., Kim, H., Jennings, W.C. Avoiding hemodialysis access-induced distal ischemia. J Vasc Access. 2020 Jul 25:1129729820943464. DOI: 10.1177/1129729820943464. Online ahead of print. PMID: 32715859.

24  Shahverdyan, R., Beathard, G., Mushtag, N., Litchfield, T.F., Nelson, P.R., Jennings, W.C. Comparison of Outcomes of Percutaneous Arteriovenous Fistulae Creation by Ellipsys and WavelinQ Devices. J Vasc Interv Radiol. 2020 Sep:31(9):1365-1372. DOI: 10.1016/j.jvir.2020.06.008. Epub 2020 Aug 11. PMID: 32792280.

25  Illig, K., Lok, C., Rajan, D., Aruny, J., Peden, E., Nelson, P., London, M., Ross, J. The role of surgery for assisted maturation after endovascular and percutaneous arteriovenous fistula creation. Journal of Vascular Access. 2020 Sep 11: doi: 10.1177/1129729820954724. PMID: 32912041.

26  Pandit, V., Nelson, P., Kempe, K., Gage, K., Zeeshan, M., Kim, H., Khan, M., Trinidad, B., Zhou, W., Tan, T.W. Racial and ethnic disparities in lower extremity amputation: Assessing the role of frailty in older adults. Surgery. 2020 Sep 8:S0039-6060(20)30458-X. doi:10.1016/j.surg.2020.07.015. PMID: 32917429.

27  Zambetti, B.R, Stiles, Z.E., Gupta, P.K. MD, Stickley, S.M., Brahmbhatt, R., Rohrer, M.J., Kempe, K. Present-day analysis of early failure after forefoot amputation. Surgery. 2020 Jul 28:S0039-6060(20)30376-7. doi: 10.1016/j.surg.2020.06.013. PMID: 32736868.

28  Martinez C, Omesiete P, Pandit V, Thompson E, Nocera M, Riall T, Guerrero M, Nfonsam V. A Protocol-Driven Reduction in Surgical Site Infections After Colon Surgery. J Surg Res. 2020 Feb;246:100-105. DOI: 10.1016/j.jss.2019.08.018. Epub 2019 Sep 26.PMID: 31563829

29   Koblinski J, Jandova J, Pandit V, Omesiete P, Nfonsam V. Disparities in colon and rectal cancer queried individually between Hispanics and Whites. J Gastrointest Oncol. 2019 Aug;10(4):632-640. DOI: 10.21037/jgo.2019.02.08. PMID: 31392043.  

30   Hanna K, Zeeshan M, Hamidi M, Pandit V, Omesiete P, Cruz A, Ewongwo A, Joseph B, Nfonsam V.  Colon cancer in the young: contributing factors and short-term surgical outcomes. Int J Colorectal Dis. 2019 Nov;34(11):1879-1885. DOI: 10.1007/s00384-019-03402-2. Epub 2019 Oct 17.PMID: 31624871.

31  Mogor O, Ewongwo A, Ojameruaye O, Pandit V, Omesiete P, Martinez C, Hsu P, Scott A, Elquza E, Nfonsam V. Rectal cancer in the young: analysis of contributing factors and surgical outcomes. J Gastrointest Oncol. 2019 Oct;10(5):896-901. DOI: 10.21037/jgo.2019.05.06. PMID: 31602327. 

32   Omesiete N, Martinez C, Pandit V, Villalvazo Y, Jecius H, Thompson E, Norcera M, Nfonsam V. Restricting Intraoperative Fluid Volume Allows Earlier Return of Bowel Function After Colon and Rectal Surgery. J Surg Res. 2019 Dec;244:130-135. DOI: 10.1016/j.jss.2019.06.013. Epub 2019 Jul 5. PMID: 31284142.

33   Palmer J, Pandit V, Zeeshan M, Kulvatunyou N, Hamidi M, Hanna K, Fain M, Nikolich-Zugich J, Zakaria ER, Joseph B. The acute inflammatory response after trauma is heightened by frailty: A prospective evaluation of inflammatory and endocrine system alterations in frailty. J Trauma Acute Care Surg. 2019 Jul;87(1):54-60. DOI: 10.1097/TA.0000000000002229. PMID: 30768559.

34   Hamidi M, Hanna K, Omesiete P, Cruz A, Ewongwo A, Pandit V, Joseph B, Nfonsam V. Does it matter where you get your surgery for colorectal cancer? Int J Colorectal Dis. 2019 Dec;34(12):2121-2127. DOI: 10.1007/s00384-019-03436-6. Epub 2019 Nov 13.PMID: 31720828. 

35   Pandit V, Lee A, Zeeshan M, Goshima K, Tan TW, Jhajj S, Trinidad B, Weinkauf C, Zhou W. Effect of frailty syndrome on the outcomes of patients with carotid stenosis. J Vasc Surg. 2020 May;71(5):1595-1600. DOI: 10.1016/j.jvs.2019.08.235. Epub 2019 Oct 24. PMID: 31668557.

36  Leon LR Jr, Green C, Labropoulos N, Pacanowski JP Jr, Jhajj S, Pandit V. Distal Retrograde Access for Infrainguinal Arterial Chronic Total Occlusions: A Prospective, Single Center, Observational Study in the Office-Based Laboratory Setting. Vasc Endovascular Surg. 2020 Nov 2:1538574420968670. doi: 10.1177/1538574420968670. Online ahead of print. PMID: 33131462.

Clinical Trials

Ellipsys Vascular Access System Post Market Surveillance (PS) Study. PI: Peter R. Nelson, MD.

Prospective, Multicenter, Single Arm Safety and Effectiveness Confirmatory Study of Endovascular Abdominal Aortic Aneurysm Repair using the Nellix® System (EVAS2 Confirmatory Study). PI: Peter R. Nelson, MD.

Prospective, multicenter, non-randomized study with consecutive, eligible subject enrollment at each site, for the evaluation of the ChEVAS System for Endovascular Repair of Paravisceral, Juxtarenal, and Pararenal Abdominal Aortic Aneurysms. PI: Peter R. Nelson, MD.

Alto™ Abdominal Stent Graft System Case Selection and Sizing Study. PI:  Dr. Hyein Kim, MD.

MIMICS-3D-USA Registry (pending) PI: Peter R. Nelson, MD.